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Post by moabiter on Aug 11, 2010 19:55:23 GMT -8
The mouse that shook the world Friday, 2 November 2007 It can run for hours at 20 metres per minute without getting tired. It lives longer, has more sex, and eats more without gaining weight. Could the science that created this supermouse be applied to humans? The mouse can run up to six kilometres (3.7 miles) at a speed of 20 metres per minute for five hours or more without stopping. Scientists said that this was equivalent of a man cycling at speed up an Alpine mountain without a break. Although it eats up to 60 per cent more food than an ordinary mouse, the modified mouse does not put on weight. It also lives longer and enjoys an active sex life well into old age – being capable of breeding at three times the normal maximum age. American scientists who created the mice – they now have a breeding colony of 500 – said that they were stunned by their abilities, especially given that the animals came about as a result of a standard genetic modification to a single metabolism gene shared with humans. They emphasised that the aim of the research was not to prepare the way to enhance the genes of people. However, they accepted that it may be possible to use the findings to develop new drugs or treatments that could one day be used to "enhance" the natural abilities of athletes. www.independent.co.uk/news/science/the-mouse-that-shook-the-world-744870.html
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Post by moabiter on Sept 8, 2010 9:56:21 GMT -8
Green mice boost genetic engineering Monday, May 17, 1999 "We want to put other genes into the mice and apply our methods to other species - that's our hope and expectation," he said. Professor Perry and his colleagues in Honolulu were the first to clone mice and to breed multiple generations of the rodents. Sperm insertionTheir new experiment involved first freeze-drying mouse sperm, then inserting DNA from another species into it and finally injecting the altered sperm into mouse eggs. news.bbc.co.uk/2/hi/science/nature/343929.stm
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Post by moabiter on Sept 8, 2010 10:00:31 GMT -8
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Post by clone on Dec 2, 2010 8:31:15 GMT -8
Scientists attach barcodes to mouse embryos – human ones coming soon 16:19 November 22, 2010 Fans of the film Blade Runner may remember a scene in which the maker of an artificial snake is identified by a microscopic serial number on one of its scales. Well, in a rare case of present-day technology actually surpassing that predicted in a movie, we’ve now gone one better – bar codes on embryos. Scientists from Spain’s Universitat Autònoma de Barcelona (UAB), along with colleagues from the Spanish National Research Council, have successfully developed an identification system in which mouse embryos and oocytes (egg cells) are physically tagged with microscopic silicon bar code labels. They expect to try it out on human embryos and oocytes soon. www.gizmag.com/barcodes-on-embryos/17017/
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Post by helpme tHE mOSUE on Jan 18, 2011 8:57:39 GMT -8
Towards a radical treatment for leukemia 14 January 2011 In 1998, Ishikawa moved to the Medical University of South Carolina in the USA, where he started his studies on humanized mice in order to analyze the human immune system using mouse models. “Mice are used in many studies to understand biology in vivo and find effective ways to overcome diseases. For example, researchers create model mice and develop particular diseases in them in place of human patients. However, the findings from mouse studies are not always applicable to medical care or drug discovery. This is why I wanted to attempt to recreate the human immune system in a mouse.” .. There are many types of blood cells, including white blood cells, red blood cells and blood platelets. White blood cells are responsible for the immune response and can be grouped into phagocytic cells, which ingest and consume foreign bodies, and lymphocyte cells, which attack foreign bodies (Fig. 1). The various types of blood cells all are produced by hematopoietic stem cells. “The exact location of hematopoietic stem cells was not clearly known, which made it difficult to extract them from surrounding tissue. I searched for molecules that could serve as markers for hematopoietic stem cells, and in doing so moved our own research forward.” www.rikenresearch.riken.jp/eng/frontline/6513
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Post by moabiter on Feb 5, 2011 17:36:38 GMT -8
Brain development may be influenced by bacteria in the gut February 1, 2011 A team of scientists from across the globe have found that gut bacteria may influence mammalian brain development and adult behavior. The study is published in the scientific journal PNAS, and is the result of an ongoing collaboration between scientists at Karolinska Institutet in Sweden and the Genome Institute of Singapore. The research team compared behavior and gene expression in two groups of mice - those raised with normal microorganisms, and those raised in the absence of microorganisms (or germ-free mice). The scientists observed that adult germ-free mice displayed different behavior from mice with normal microbiota, suggesting that gut bacteria may have a significant effect on the development of the brain in mammals. www.physorg.com/news/2011-02-brain-bacteria-gut.html
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Post by i on May 8, 2011 16:50:22 GMT -8
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Post by clone on Nov 2, 2012 22:41:23 GMT -8
Transfusion of young blood could delay onset of diseases like Alzheimer's 10:00PM BST 17 Oct 2012 <SNIP> It means people in their 40s or 50s could in future be given blood donated by someone in their early twenties to prevent their brain from deteriorating and stave off diseases like Alzheimer's. Researchers from Stanford University found that old mice given transfusions of younger blood performed better in a memory task than those left to age naturally. They also began to re-grow connections in their brains which had previously begun to disappear as part of the aging process and which affect memory. A previous study had already established the opposite - that young mice given a transfusion of blood from older mice began to show signs of premature aging in their brains. www.telegraph.co.uk/health/9615779/Transfusion-of-young-blood-could-delay-onset-of-diseases-like-Alzheimers.html
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Post by clone on Nov 5, 2012 7:37:17 GMT -8
1 November 2012 Last updated at 11:43 ET Hurricane Sandy: Thousands of rodents drown at NY lab Thousands of lab rodents have drowned after storm Sandy caused flooding at a university centre in New York. The genetically modified mice and rats were being used to study illnesses such as heart disease, cancer, autism and schizophrenia. The animal colonies at the Smilow Research Center in Kips Bay were considered among the most important of their type in the US. more: www.bbc.co.uk/news/science-environment-20172256
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Post by clone on Nov 5, 2012 8:14:17 GMT -8
Beyond the biomedical model. Broadcast: Sunday 4 November 2012 5:05PM There was a time when schizophrenia was blamed on the family and the so-called schizophrenogenic mother. Then with the growth of knowledge about the biology of mental illness all hope was pinned on the development of the perfect medication. Now social factors are seen as part of the cause and should be part of the cure. Lynne Malcolm hosts this discussion on the art and science of schizophrenia at the Dax Centre in Melbourne. Guests Brendon Clarke, Mental health advocate from the Mental Illness Fellowship Victoria Professor Brian Dean, Schizophrenia researcher with the CRC for Mental Health Professor Jayashri Kulkarni, Professor of Psychiatry and Director of the Monash Alfred Psychiatry Research Centre Emma Last, Education manager with the Dax Centre, Art gallery www.abc.net.au/radionational/programs/allinthemind/art2c-science-and-schizophrenia/4340806
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